In-vivo Blood Glucose Control by Phenolic Compound from Vernonia amygdalina, Andrographis paniculata, and Pithecellobium jiringa in Streptozotoxin-Induced Diabetic Rats
نویسنده
چکیده
Article history: Received 25 June 2014 Received in revised form 8 July 2014 Accepted 14 September 2014 Available online 27 September 2014
منابع مشابه
Anti-Hyperglycemic and Renal Protective Activities of Andrographis paniculata Roots Chloroform Extract
The chloroform extract of Andrographis paniculata roots was tested for its antihyperglycemic activity in alloxan induced diabetic rats using chronic and acute studies. The blood glucose lowering activity was determined after oral administration at doses of 50, 100 and 150 mg/kg body weight in acute study. Where as in case of chronic study blood glucose, protein, albumin and creatinine levels ...
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The aim of present study was to investigate the potential roles of ethanolic and hot water extracts of Andrographis paniculata on reducing the blood sugar level (BSL) in alloxaninduced rats. Oral administration of ethanolic (2 g/kg b. w.) and hot water (0.8 g/kg b. w.) extracts of Andrographis paniculata showed the antidiabetic properties and decreased the blood glucose level by 33.71% (p<0.000...
متن کاملModulatory effects of dietary supplementation by Vernonia amygdalina on high-fat-diet-induced obesity in Wistar rats.
BACKGROUND Obesity is a growing public health problem arising from energy imbalance. The effect of 10% dietary incorporation of Vernonia amygdalina (VA) leaves into high-fat diets on some biological markers of adiposity and dyslipidaemia was investigated. METHODS Experimental diets consisted of the following – CD (control diet); HFD (high-fat diet); and HFD- VA (HFD containing 10% Verno...
متن کاملRegular paper In vitro α-glucosidase and α-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide
There has been an enormous interest in the development of alternative medicines for type 2 diabetes, specifically screening for phytochemicals with the ability to delay or prevent glucose absorption. The goal of the present study was to provide in vitro evidence for potential inhibition of α-glucosidase and α-amylase enzymes, followed by a confirmatory in vivo study on rats to generate a strong...
متن کاملAnti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats.
Andrographis paniculata is an annual herb and widely cultivated in Southeast Asian countries for its medicinal use. In recent investigations, A. paniculata was found to be effective against Type 1 diabetes mellitus (Type 1 DM). Here, we used a non-genetic out-bred Sprague-Dawley rat model to test the antidiabetic activity of A. paniculata against Type 2 diabetes mellitus (Type 2 DM). Proton Nuc...
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